Name | Milbemycin oxime |
Synonyms | Milbemite CGA-179246 Milbemycin oxime Milbemycin, oxime Milbemycin oxime CRS Milbemycin A, 5-oxime Milbemycin Oxime (200 mg) Milbemycin oxime fandachem Milbemycin Oxime (1443806) Milbemycin Oxime (Mixture of Milbemycin Oxime A3 and A4) |
CAS | 129496-10-2 |
EINECS | 206-141-6 |
InChI | InChI=1/C32H45NO7.C31H43NO7/c1-6-27-21(4)12-13-31(40-27)17-25-16-24(39-31)11-10-20(3)14-19(2)8-7-9-23-18-37-29-28(33-36)22(5)15-26(30(34)38-25)32(23,29)35;1-18-7-6-8-23-17-36-28-27(32-35)21(4)14-26(31(23,28)34)29(33)37-25-15-24(10-9-19(2)13-18)39-30(16-25)12-11-20(3)22(5)38-30/h7-10,15,19,21,24-27,29,35-36H,6,11-14,16-18H2,1-5H3;6-9,14,18,20,22,24-26,28,34-35H,10-13,15-17H2,1-5H3/b8-7+,20-10+,23-9+,33-28-;7-6+,19-9+,23-8+,32-27-/t19-,21-,24+,25-,26-,27+,29+,31+,32+;18-,20-,22+,24+,25-,26-,28+,30-,31+/m00/s1 |
InChIKey | LKMMLHTWKLEARD-MGZQXKBQSA-N |
Molecular Formula | 2C32H45NO7.2C31H43NO7 |
Molar Mass | 2194.78 |
Melting Point | 169.6-177.4° |
Flash Point | 412℃ |
Storage Condition | 2-8℃ |
UN IDs | 2588 |
WGK Germany | 3 |
HS Code | 2932206000 |
Hazard Class | 6.1(b) |
Packing Group | III |
Toxicity | LD50 orally in mice: 1000-1500 mg/kg (Ciba-Geigy) |
overview | milbemime (MilbemycinOxime) is a macrolide antibody internal and external parasite drug, and is an oxime derivative of milbemycin A3 and A4. |
application | in 1997, Taiwan region of China introduced the double pulse heart with milbbe oxime as the main component produced by Taiwan Novartis co., ltd. as an internal medicine for preventing heartworm and intestinal parasites in dogs and cats, which is the first application of milbbe oxime in China. Milbexime has a broad-spectrum anti-parasitic effect, and has a good repellent effect on in vivo and in vitro parasites, especially nematodes and arthropods. |
biological activity | Milbemycin Oxime is a broad-spectrum antiparasitic drug with active effects on worms and mites. |